Management of a Chronic Radiation Necrosis Wound with Lyopreserved Placental Membrane Containing Viable Cells

Radiation therapy is commonly employed in the treatment of various cancers alone, or in a combination with surgical tumor excision, with the purpose of selectively killing cancer cells at the tumor site.1 Radiation therapy, however, is damaging to the surrounding healthy tissue and may result in tissue necrosis. Radiation can also compromise wound healing leading…

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Biofilm-hijacked Inflammation: The Missing Link to Hard-to-heal Wounds

Diabetic foot ulcers (DFUs), venous leg ulcers (VLUs), and pressure ulcers (PUs) represent the most common hard-toheal wounds. According to Armstrong,1 “Every 1.2 seconds, someone develops a diabetic ulcer; every 20 seconds, someone is amputated.” In the United States, $1 million is spent every 30 seconds on diabetic foot complications.2,3 The news is similar for…

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Early Weight-Bearing After Arthrodesis of the First Metatarsal-PhalangealJoint: A Systematic Review of the Incidence of Non-Union

Arthrodesis of thefirst metatarsal-phalangeal joint is a reliable procedure for correction of both hallux limitus/rig-idus and severe hallux abducto valgus deformities. However, 1 potential contraindication to the procedure is theextended period of non-weight-bearing immobilization that is typically associated with the postoperative course.The objective of this investigation was to perform a systematic review of the incidence…

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The Role of Stem Cells in Wound Healing: An Overview

The evolution of stem cells in the chronic wound regimen has taken a very circuitous path, so to speak. This article will briefly describe some of the different types of stem cells and how they may be utilized as therapeutic modalities in healthcare, including specifically in wound care. TYPES OF STEM CELLS When we talk…

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Diabetic Driving Studies—Part 1: Brake Response Time in Diabetic Drivers With Lower Extremity Neuropathy

Although the effect of lower extremity pathology and surgical intervention on automobile driving function has been a topic of contemporary interest, we are unaware of any analysis of the effect of lower extremity diabetic sensorimotor neuropathy on driving performance. The objective of the present case-control investigation was to assess the mean brake response time in…

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First Metatarsal Head and Medial Eminence Widths with and Without Hallux Valgus

Resection of the medial eminence in bunioncorrection surgery is commonly performed and welldescribed. In 1923, Silver1described using a chiselto remove a thin layer of cortex, along withperiosteum and any exostoses, from the medialaspect of the first metatarsal head for treatment ofhallux valgus. In 1928, McBride2described aconservative operation for bunions that focusedon correcting muscle contracture and…

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